Genetics and embryological mechanisms of congenital heart diseases
نویسندگان
چکیده
منابع مشابه
Genetics and embryological mechanisms of congenital heart diseases.
Developmental genetics of congenital heart diseases has evolved from analysis of embryo sections towards molecular genetics of cardiac morphogenesis with a dynamic view of cardiac development. Lineage analysis, transgenic animal models and retrospective clonal analysis of the developing heart led to identification of different cardiac lineages and their respective roles. Genetics of congenital ...
متن کاملGenetics of Congenital Heart Disease
Congenital heart defects are present in 1% of all live births and are a significant burden on the parents and family, healthcare system, and overall community. Congenital heart defects (CHD) are also identified in 10% of still births and are presumed to be a substantial cause of early fetal demise. With advances in prenatal diagnosis, corrective strategies, and longitudinal care, infant mortali...
متن کاملGenetics of Congenital Heart Disease
Genetics of Congenital Heart Disease: The Glass Half Empty Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/CIRCRESAHA.112.300853 2013;112:707-720 Circ Res. http://circres.ahajournals.org/content/112/4/707 ...
متن کاملGenetics of Congenital Heart Disease
Cardiovascular malformations are the most common type of birth defect and result in significant mortality worldwide. The etiology for the majority of these anomalies remains unknown but genetic factors are being recognized as playing an increasingly important role. Advances in our molecular understanding of normal heart development have led to the identification of numerous genes necessary for ...
متن کاملGenetics and Genomics of Congenital Heart Disease.
Congenital heart disease is the most common birth defect, and because of major advances in medical and surgical management, there are now more adults living with congenital heart disease (CHD) than children. Until recently, the cause of the majority of CHD was unknown. Advances in genomic technologies have discovered the genetic causes of a significant fraction of CHD, while at the same time po...
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases
سال: 2009
ISSN: 1875-2136
DOI: 10.1016/j.acvd.2008.06.020